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Home >> Antibodies >> KLK7 Antibody / Kallikrein 7

KLK7 Antibody / Kallikrein 7 [clone KLK7/4691] (V4649)

  Catalog No Formulation Size Price (USD)  
Image V4649-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4649-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4649SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Analysis of a HuProt(TM) microarray containing more than 19,000 full-length human proteins using KLK7 antibody (clone KLK7/4691) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a mAb to its intended target. A mAb is considered to specific to its intended target, if the mAb has an S-score of at least 2.5. For example, if a mAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that mAb to protein X is equal to 29.
IHC staining of FFPE human skin tissue with KLK7 antibody (clone KLK7/4691). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name KLK7/4691
Purity Protein A/G affinity
UniProt P49862
Localization Secreted
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This KLK7 antibody is available for research use only.
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Description

KLK7/Kallikrein 7 may catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface as well as play a role in the activation of precursors to inflammatory cytokines. [UniProt]

Application Notes

Optimal dilution of the KLK7 antibody should be determined by the researcher.

Immunogen

A recombinant fragment of human KLK7 protein (within amino acids 1-200) was used as the immunogen for the KLK7 antibody.

Storage

Aliquot the KLK7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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