- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
KDR Antibody / Kinase Insert Domain Receptor / VEGFR2 (F50627)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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F50627-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F50627-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P35968 |
| Localization | Cytoplasmic and cell surface |
| Applications | Western blot : 1:1000 Flow Cytometry : 1:10-1:50 |
| Limitations | This KDR antibody is available for research use only. |
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KDR is a major growth factor for endothelial cells. This protein encodes one of the two receptors of the KDR. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..
Titration of the KDR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1153-1182 from the human protein was used as the immunogen for this KDR antibody.
Aliquot the KDR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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