- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Titration of the ISL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 156-185 from the human protein was used as the immunogen for this ISL1 antibody.
Aliquot the ISL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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