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Home >> Antibodies >> IRF1 Antibody / Interferon Regulatory Factor 1

IRF1 Antibody / Interferon Regulatory Factor 1 (F41210)

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  Catalog No Formulation Size Price (USD)  
Image F41210-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F41210-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IRF1 antibody western blot analysis in human MDA-MB-231 cell lysate. Expected molecular weight: ~37 kDa (unmodified), 45-50 kDa (modified).
IRF1 antibody western blot analysis in human MDA-MB-231 cell lysate. Expected molecular weight: ~37 kDa (unmodified), 45-50 kDa (modified).
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P10914
Applications Western blot : 1:1000
Limitations This IRF1 antibody is available for research use only.
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Description

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Application Notes

Titration of the IRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 260-286 from the human protein was used as the immunogen for this IRF1 antibody.

Storage

Aliquot the IRF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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