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Home >> Antibodies >> Interleukin-2 Antibody / IL-2

Interleukin-2 Antibody / IL-2 [clone IL2/8712] (V5064)

  Catalog No Formulation Size Price (USD)  
Image V5064-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V5064-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V5064SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name IL2/8712
Purity Protein A/G affinity
UniProt P60568
Localization Secreted
Applications ELISA (Order BSA-free format for coating) :
Flow cytometry : 1-2ug/million cells
Limitations This Interleukin-2 antibody is available for research use only.
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Description

Interleukin-2 (IL-2) is a T cell stimulatory cytokine that induces T cell proliferation and NK cell proliferation and activation. Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL-2 induces CTLA-4 and also functions as a survival factor for lymphocytes.

Application Notes

Optimal dilution of the Interleukin-2 antibody should be determined by the researcher.

Immunogen

A recombinant fragment of human IL2 protein was used as the immunogen for the Interleukin-2 antibody.

Storage

Aliquot the Interleukin-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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