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Home >> Antibodies >> Integrin beta 1 Antibody / ITGB1 / CD29

Integrin beta 1 Antibody / ITGB1 / CD29 [clone 1084CT17.4.1] (F52411)

  Catalog No Formulation Size Price (USD)  
Image F52411-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52411-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Integrin beta 1 antibody western blot analysis in U87-MG lysate. Predicted molecular weight: 88/130~150 kDa (unmodified/glycosylated).
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 1084CT17.4.1
Purity Purified
UniProt P05556
Applications Western blot : 1:1000
Limitations This Integrin beta 1 antibody is available for research use only.
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Description

Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. Integrins link the actin cytoskeleton with the extracellular matrix and they transmit signals bidirectionally between the extracellular matrix and cytoplasmic domains. Beta-integrins are primarily responsible for targeting integrin dimers to the appropriate subcellular locations, which in adhesive cells is mainly focal adhesions. Integrin beta-1 mutants lose the ability to target to sites of focal adhesions. [Wiki]

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Integrin beta 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Purified His-tagged protein was used to produced this monoclonal Integrin beta 1 antibody.

Storage

Store at 4oC for up to one month. For long term, aliquot the Integrin beta 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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