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Home >> Antibodies >> Integrin alpha V Antibody / ITGAV / Vitronectin Receptor

Integrin alpha V Antibody / ITGAV / Vitronectin Receptor [clone CCE-9] (RQ5163)

  Catalog No Formulation Size Price (USD)  
Image RQ5163 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human A549 cell lysate with Integrin alpha V antibody. Expected molecular weight: 116-150 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name CCE-9
Purity Affinity purified
UniProt P06756
Applications Western blot : 1:1000-1:2000
Limitations This Integrin alpha V antibody is available for research use only.
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Description

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [RefSeq]

Application Notes

Optimal dilution of the Integrin alpha V antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Integrin alpha V / ITGAV was used as the immunogen for the Integrin alpha V antibody.

Storage

Store the Integrin alpha V antibody at -20oC.

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