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Home >> Antibodies >> IL1R2 Antibody

IL1R2 Antibody (F41147)

  Catalog No Formulation Size Price (USD)  
Image F41147-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F41147-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IL1R2 antibody western blot analysis in WiDr lysate. Predicted molecular weight ~ 45 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P27930
Applications Western blot : 1:1000
Limitations This IL1R2 antibody is available for research use only.
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Description

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.

Application Notes

Titration of the IL1R2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 273-300 from the human protein was used as the immunogen for this IL1R2 antibody.

Storage

Aliquot the IL1R2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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