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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
Titration of the IL1R2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 273-300 from the human protein was used as the immunogen for this IL1R2 antibody.
Aliquot the IL1R2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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