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Home >> Antibodies >> IL-4 Antibody

IL-4 Antibody (RQ4162)

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  Catalog No Formulation Size Price (USD)  
Image RQ4162 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human CCRF-CEM cell lysate with IL-4 antibody at 0.5ug/ml. Expected molecular weight: 14-20 kDa depending on glycosylation level.
Western blot testing of human CCRF-CEM cell lysate with IL-4 antibody at 0.5ug/ml. Expected molecular weight: 14-20 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P05112
Applications Western Blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This IL-4 antibody is available for research use only.
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Description

Interleukin-4 (IL-4), also known as a B-cell stimulatory factor1 (BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells.1 The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. The mouse and human genes and their protein products show structural and functional similarities.

Application Notes

Optimal dilution of the IL-4 antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids H25-S153 was used as the immunogen for the IL-4 antibody.

Storage

After reconstitution, the IL-4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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