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Home >> Antibodies >> IL-34 Antibody

IL-34 Antibody (RQ4931)

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  Catalog No Formulation Size Price (USD)  
Image RQ4931 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human placenta, 2) rat brain and 3) mouse brain lysate with IL-34 antibody at 0.5ug/ml. Predicted molecular weight ~26 kDa, secreted as an ~39 kDa homodimer that may be glycosylated.
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Western blot testing of 1) human placenta, 2) rat brain and 3) mouse brain lysate with IL-34 antibody at 0.5ug/ml. Predicted molecular weight ~26 kDa, secreted as an ~39 kDa homodimer that may be glycosylated.
IHC staining of FFPE human tonsil tissue with IL-34 antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
IHC staining of FFPE mouse spleen tissue with IL-34 antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q6ZMJ4
Localization Secreted
Applications Western blot : 0.5-1ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This IL-34 antibody is available for research use only.
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  • Applications : WB, IHC-P, Direct ELISA
    Reactivity : Human

Description

Interleukin 34 (IL-34) is a protein belonging to a group of cytokines called interleukins. It was originally identified in humans, by large scale screening of secreted proteins; chimpanzee, murine, rat and chicken interleukin 34 orthologs have also been found. The protein is composed of 241 amino acids, 39 kilodaltons in mass, and forms homodimers. IL-34 increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. This gene is mapped to 16q22.1.

Application Notes

Optimal dilution of the IL-34 antibody should be determined by the researcher.

Immunogen

Amino acids NEPLEMWPLTQNEECTVTGFLRDKLQYR from the human protein were used as the immunogen for the IL-34 antibody.

Storage

After reconstitution, the IL-34 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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