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Home >> Antibodies >> IL-23 Antibody (p19/alpha subunit)

IL-23 Antibody (p19/alpha subunit) (RQ4068)

  Catalog No Formulation Size Price (USD)  
Image RQ4068 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) placenta, 2) PANC-1, 3) rat lymph, 4) rat small intestine, 5) rat testis, 6) rat ovary, and 7) mouse testis lysate with IL-23 antibody at 0.5ug/ml. Predicted molecular weight ~21 kDa, observed molecular weight ~19 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q9NPF7
Applications Western Blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This IL-23 antibody is available for research use only.
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Description

Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. IL-23, also known as Interleukin-23 subunit alphainin (IL23A), is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.

Application Notes

Optimal dilution of the IL-23 antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein corresponding to amino acids R20-R178 was used as the immunogen for the IL-23 antibody.

Storage

After reconstitution, the IL-23 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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