- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
IL-13 Antibody (R30541)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R30541 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| UniProt | P42203 |
| Applications | Western blot : 0.5-1ug/ml |
| Limitations | This IL-13 antibody is available for research use only. |
|
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Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. This cytokine is secreted by many cell types, but especially T helper type 2(Th2) cells that is an important mediator of allergic inflammation and disease. The gene is mapped to 5q23-q31. It induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor(IL-4Ralpha) and at least one of two known IL-13-specific binding chains. It acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
The stated application concentrations are suggested starting amounts. Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the middle region of rat IL-13 (CNAIHRTQRILNGLCNQKASDVA) was used as the immunogen for this IL-13 antibody.
After reconstitution, the IL-13 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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