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Home >> Antibodies >> IL-13 Antibody

IL-13 Antibody (F43210)

  Catalog No Formulation Size Price (USD)  
Image F43210-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F43210-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IL-13 antibody western blot analysis in NCI-H460 lysate. Expected molecular weight: 16-35 kDa depending on level of glycosylation.
Confocal immunofluorescent analysis of IL-13 antibody with NCI-H460 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
IL-13 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P35225
Applications Western blot : 1:1000
Immunofluorescence : 1:10-1:50
IHC (Paraffin) : 1:10-1:50
Limitations This IL-13 antibody is available for research use only.
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Description

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].

Application Notes

Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 118-146 from the human protein was used as the immunogen for this IL-13 antibody.

Storage

Aliquot the IL-13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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