- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
IKK alpha/beta Antibody [clone FCC-3] (RQ4722)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ4722 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | FCC-3 |
| Purity | Affinity purified |
| UniProt | O15111 |
| Applications | Western blot : 1:500-1:1000 |
| Limitations | This IKK alpha/beta antibody is available for research use only. |
|
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The IkappaB kinase complex is composed of three subunits each encoded by a separate gene: IKK alpha (also known as IKK1 and CHUK), IKK beta (also known as IKK2 and IKBKB), and IKK gamma (also known as NEMO/ and IKBKG). The alpha- and beta- subunits together are catalytically active whereas the gamma-subunit serves a regulatory function. The IKKa and IKKb kinase subunits are homologous in structure, composed of a kinase domain, as well as leucine zipper and helix-loop-helix dimerization domains, and a carboxy-terminal NEMO-binding domain (NBD). [Wiki]
Optimal dilution of the IKK alpha/beta antibody should be determined by the researcher.
A synthetic peptide amino acid sequence specifc for and common to human IKK alpha and beta was used as the immunogen for the IKK alpha/beta antibody.
Store the IKK alpha/beta antibody at -20oC.
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