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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.
Differences in protocols and secondary/substrate sensitivity may require the HVEM antibody to be titrated for optimal performance.
Amino acids L39-V202 from the human protein were used as the immunogen for the HVEM antibody.
After reconstitution, the HVEM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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