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Home >> Antibodies >> HVEM Antibody / TNFRSF14

HVEM Antibody / TNFRSF14 (R32572)

  Catalog No Formulation Size Price (USD)  
Image R32572 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) HeLa and 2) SW620 cell lysate with HVEM antibody at 0.5ug/ml. Expected molecular weight: 30-38 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q92956
Applications Western blot : 0.5-1ug/ml
ELISA : 0.5-1ug/ml (human protein tested); request BSA-free format for coating
Limitations This HVEM antibody is available for research use only.
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Description

Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.

Application Notes

Differences in protocols and secondary/substrate sensitivity may require the HVEM antibody to be titrated for optimal performance.

Immunogen

Amino acids L39-V202 from the human protein were used as the immunogen for the HVEM antibody.

Storage

After reconstitution, the HVEM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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