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Home >> Antibodies >> HLA-ABC Antibody (MHC I)

HLA-ABC Antibody (MHC I) [clone 246-B8.E7] (V2569)

  Catalog No Formulation Size Price (USD)  
Image V2569-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2569-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2569SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Western blot testing of ThP-1 cell lysate with HLA-ABC antibody. Expected molecular weight of A/B/C: 40-41 kDa.
SDS-PAGE Analysis of Purified, BSA-Free HLA-ABC Antibody (clone 246-B8.E7). Confirmation of Integrity and Purity of the Antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name 246-B8.E7
Purity Protein G affinity chromatography
UniProt P30443 , P01889 , P30499
Localization Cell surface
Applications Western blot : 1-2ug/ml
Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Limitations This HLA-ABC antibody is available for research use only.
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Description

Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Application Notes

Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

Immunogen

Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.

Storage

Store the HLA-ABC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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