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  • Email: info@nsjbio.com
Home >> Antibodies >> HIF1A Antibody

HIF1A Antibody (F47799)

  Catalog No Formulation Size Price (USD)  
F47799-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 299

F47799-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 125
HIF1A antibody western blot analysis in A549 lysate. Routinely observed molecular weight: 100~120 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q16665
Localization Nuclear, possible cytoplasmic
Applications Western blot : 1:1000
Limitations This HIF1A antibody is available for research use only.

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Description

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

Application Notes

Titration of the HIF1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 735-762 from the human protein was used as the immunogen for this HIF1A antibody.

Storage

Aliquot the HIF1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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