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Home >> Antibodies >> HER4 Antibody

HER4 Antibody (F50604)

  Catalog No Formulation Size Price (USD)  
Image F50604-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F50604-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of ErbB4 / HER4 antibody and HL-60 cell lysate. Predicted molecular weight: 147-180 kDa (precursor), 120, 80 kDa (cleaved forms).
IHC analysis of FFPE human breast carcinoma tissue stained with the HER4 antibody
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q15303
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This HER4 antibody is available for research use only.
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Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Application Notes

Titration of the HER4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 25-55 from the human protein was used as the immunogen for this HER4 antibody.

Storage

Aliquot the HER4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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