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Home >> Antibodies >> HDAC2 Antibody

HDAC2 Antibody (F51899)

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  Catalog No Formulation Size Price (USD)  
Image F51899-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F51899-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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HDAC2 antibody western blot analysis in SH-SY5Y lysate. Predicted molecular weight: 55-60 kDa.
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HDAC2 antibody western blot analysis in SH-SY5Y lysate. Predicted molecular weight: 55-60 kDa.
HDAC2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma
HDAC2 antibody flow cytometric analysis of K562 cells (right histogram) compared to a negative control (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Fluorescent confocal image of HeLa cell stained with HDAC2 antibody at 1:25. HDAC2 immunoreactivity is localized to the nucleus.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Chicken
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q92769
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Immunofluorescence : 1:10-1:50
Limitations This HDAC2 antibody is available for research use only.
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Description

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Application Notes

Titration of the HDAC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 410-439 from the human protein was used as the immunogen for this HDAC2 antibody.

Storage

Aliquot the HDAC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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