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- Email: info@nsjbio.com
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Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
Titration of the Gsk3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 30-59 from the mouse protein was used as the immunogen for this Gsk3b antibody.
Aliquot the Gsk3b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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