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Home >> Antibodies >> GLUT5 Antibody (Glucose Transporter 5)

GLUT5 Antibody (Glucose Transporter 5) (R31175)

  Catalog No Formulation Size Price (USD)  
Image R31175 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Glut5 antbody; Lane 1: U87; 2: 293T; 3: HT1080; 4: SW620 cell lysate. Expected/observed molecular weight ~55 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P22732
Localization Cytoplasmic, membranous
Applications Western blot : 0.5-1ug/ml
Limitations This GLUT5 antibody is available for research use only.
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Description

SLC2A5, also known as Glucose transporter 5, is a fructose transporter expressed on the apical border of enterocytes in the small intestine. The gene is located on chromosome 1. The protein allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructoses high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue, and brain. Along with GLUT7, -9 and -11, GLUT5 is a class II glucose transporter family member. Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient.

Application Notes

The stated application concentrations are suggested starting points. Titration of the GLUT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids 481-501 (VSEVYPEKEELKELPPVTSEQ-human) were used as the immunogen for this GLUT5 antibody.

Storage

After reconstitution, the GLUT5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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