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Home >> Antibodies >> Glucagon Antibody

Glucagon Antibody [clone 329CT36.10.10] (F40290)

  Catalog No Formulation Size Price (USD)  
Image F40290-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40290-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot analysis of lysate from (1) HT29 and (2) HepG2 cell line using Glucagon antibody at 1:1000. Predicted molecular weight ~21 kDa (pro form).
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, k
Clone Name 329CT36.10.10
Purity Purified
UniProt P01275
Applications Western blot : 1:1000
Limitations This Glucagon antibody is available for research use only.
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Description

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Application Notes

Titration of the Glucagon antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 119-148 from the human protein was used as the immunogen for this Glucagon antibody.

Storage

Aliquot the Glucagon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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