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- Email: info@nsjbio.com
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Glucagon-like peptide-1 (GLP-1) is a 30 amino acid long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon peptide. It is produced and secreted by intestinal enteroendocrine L-cells and certain neurons within the nucleus of the solitary tract in the brainstem upon food consumption. The initial product GLP-1 (1-37) is susceptible to amidation and proteolytic cleavage which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7-36) amide and GLP-1 (7-37). Active GLP-1 composes two alpha-helices from amino acid position 13-20 and 24-35 separated by a linker region. [Wiki]
Optimal dilution of the GLP-1 antibody should be determined by the researcher.
A synthetic peptide specific to human Glucagon-like peptide 1 was used as the immunogen for the GLP-1 antibody.
Store the GLP-1 antibody at -20oC.
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