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Home >> Antibodies >> GLP-1 Antibody / Glucagon-like peptide 1

GLP-1 Antibody / Glucagon-like peptide 1 [clone AOHH-7] (RQ4965)

  Catalog No Formulation Size Price (USD)  
Image RQ4965 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human fetal pancreas with GLP-1 antibody. Predicted molecular weight ~3 kDa but can be observed at up to ~21 kDa depending on Proglucagon cleavage.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AOHH-7
Purity Affinity purified
UniProt P01275
Applications Western blot : 1:1000-1:5000
Limitations This GLP-1 antibody is available for research use only.
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Description

Glucagon-like peptide-1 (GLP-1) is a 30 amino acid long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon peptide. It is produced and secreted by intestinal enteroendocrine L-cells and certain neurons within the nucleus of the solitary tract in the brainstem upon food consumption. The initial product GLP-1 (1-37) is susceptible to amidation and proteolytic cleavage which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7-36) amide and GLP-1 (7-37). Active GLP-1 composes two alpha-helices from amino acid position 13-20 and 24-35 separated by a linker region. [Wiki]

Application Notes

Optimal dilution of the GLP-1 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Glucagon-like peptide 1 was used as the immunogen for the GLP-1 antibody.

Storage

Store the GLP-1 antibody at -20oC.

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