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Home >> Antibodies >> GLIS3 Antibody / GLI-similar 3 / ZNF515

GLIS3 Antibody / GLI-similar 3 / ZNF515 (RQ7338)

  Catalog No Formulation Size Price (USD)  
Image RQ7338 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human A549, 2) rat kidney, 3) rat brain, 4) mouse kidney and 5) mouse brain tissue lysate with GLIS3 antibody. Predicted molecular weight ~84 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q8NEA6
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This GLIS3 antibody is available for research use only.
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Description

Zinc finger protein GLI3 is a protein that in humans is encoded by the GLI3 gene. This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

Application Notes

Optimal dilution of the GLIS3 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids A184-P765) was used as the immunogen for the GLIS3 antibody.

Storage

After reconstitution, the GLIS3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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