• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> GITR Antibody / TNFRSF18

GITR Antibody / TNFRSF18 (RQ4383)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image RQ4383 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Western blot testing of human placenta lysate with E2F2 antibody at 0.5ug/ml. Predicted molecular weight: 47-52 kDa, observed here at ~70 kDa.
Western blot testing of human 1) Jurkat and 2) K562 cell lysate with GITR antibody at 0.5ug/ml. Predicted molecular weight ~26 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q9Y5U5
Localization Cell membrane
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml (human recombinant protein)
Limitations This GITR antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

Description

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR, is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Application Notes

Optimal dilution of the GITR antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids Q26-P162 was used as the immunogen for the TNFRSF18 antibody.

Storage

After reconstitution, the GITR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.