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Home >> Antibodies >> GALT Antibody / Galactose-1-phosphate uridyltransferase

GALT Antibody / Galactose-1-phosphate uridyltransferase (RQ4086)

  Catalog No Formulation Size Price (USD)  
Image RQ4086 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) HepG2 and 2) MCF7 cell lysate with GALT antibody at 0.5ug/ml. Predicted molecular weight ~43 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P07902
Applications Western Blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This GALT antibody is available for research use only.
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Description

Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.

Application Notes

Optimal dilution of the GALT antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein corresponding to amino acids Q188-A379 was used as the immunogen for the GALT antibody.

Storage

After reconstitution, the GALT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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