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- Email: info@nsjbio.com
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This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
Optimal dilution of the FCGRT antibody should be determined by the researcher.
A recombinant human partial protein (amino acids 24-215) was used as the immunogen for the FCGRT antibody.
Store the FCGRT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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