- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
The stated application concentrations are suggested starting points. Titration of the Factor XIIIa antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 60-94 from human Factor XIIIa was used as the immunogen for the Factor XIIIa antibody.
Aliquot the Factor XIIIa antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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