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- Email: info@nsjbio.com
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Importins and exportins are transport receptors carrying cargo molecules into and out of the nucleus. Exportin 4 is a member of the Importin B superfamily of RanGTP-binding proteins. Its homology to other family members is restricted to its N-terminal RanGTP-binding motif. Exportin 4 is a nuclear export receptor for eIF-5A, a protein involved in the cellular stress response, functioning as a regulator of p53-mediated and TNF-alpha-mediated apoptosis.
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
A recombinant protein fragment from the C-terminal portion of Exportin 4 was used as the immunogen for this antibody.
Aliquot the Exportin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Exp4, XPO4
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