- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ErbB2 Antibody / HER2 (F54939)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54939-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F54939-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P04626 |
| Applications | Immunohistochemistry (FFPE) : 1:50-1:100 Western blot : 1:500-1:1000 |
| Limitations | This ErbB2 antibody is available for research use only. |
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ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, althought neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
The stated application concentrations are suggested starting points. Titration of the ErbB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1206-1236 from the human protein was used as the immunogen for the ErbB2 antibody.
Aliquot the ErbB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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