ER Antibody ER506 | V2113 NSJ Bioreagents

	Catalog No	Formulation	Size	Price (USD)
	V2113-100UG	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide	100 ug	519
Formulation
	V2113-20UG	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide	20 ug	229
Formulation
	V2113SAF-100UG	1 mg/ml in 1X PBS; BSA free, sodium azide free	100 ug	519
Formulation

›

IHC testing of FFPE human endometrium with ER antibody (clone ER506).

Intracellular FACS testing of human MCF-7 cells: Black=cells alone; Green=isotype control; Red= PE conjugated ER antibody (V2113PE)

Western blot testing of MCF-7 cell lysate with ER antibody (clone ER506). Predicted molecular weight of ER alpha: ~67 kDa.

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using ER antibody (clone ER506). These results demonstrate the foremost specificity of the ER506 mAb.
Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

SDS-PAGE analysis of purified, BSA-free ER antibody (clone ER506) as confirmation of integrity and purity.

Species Reactivity	Human
Format	Purified
Clonality	Monoclonal (mouse origin)
Isotype	Mouse IgG1, kappa
Clone Name	ER506
Purity	Protein G affinity chromatography
Gene ID	2099
Localization	Intracellular, Nuclear
Applications	Flow cytometry : 1-2ug/10^6 cells Western blot : 1-2ug/ml Immunohistochemistry (FFPE) : 1-2ug/ml (1)
Limitations	This ER antibody is available for research use only.
	Review this product on BioCompare and get a $20 Amazon gift card

Description

Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. ER presence in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. Clone ER506 antibody strongly stains nuclei of epithelial cells in breast carcinomas.