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Home >> Antibodies >> EPO Antibody

EPO Antibody (R30106)

  Catalog No Formulation Size Price (USD)  
Image R30106 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of EPO antibody and Lane 1: Recombinant human protein 10ng; 2: 5ng; 3: 2.5ng. Predicted molecular weight: 18-34 kDa depending on glycosylation level.
IHC-P: EPO antibody testing of human placenta tissue
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 0.025% sodium azide
UniProt P01588
Applications Western blot (recombinant protein) : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
ELISA : 0.1-0.5ug/ml (human protein tested)
Limitations This EPO antibody is available for research use only.
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Description

EPO, Erythropoietin, is an acidic glycoprotein hormone with a molecular mass of 34 kD. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow. This gene is mapped to 7q22.1. It is produced by interstitial fibroblasts in the kidney in close association with peritubular capillary and tubular epithelial cells. It is also produced in perisinusoidal cells in the liver. While liver production predominates in the fetal and perinatal period, renal production is predominant during adulthood. As the prime regulator of red cell production, its major functions are to promote erythroid differentiation and to initiate hemoglobin synthesis. It also has other known biological functions. For example, erythropoietin plays an important role in the brains response to neuronal injury. EPO is also involved in the wound healing process.

Application Notes

The stated application concentrations are suggested starting points. Titration of the EPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human partial recombinant protein (AA 1-166) was used as the immunogen for this EPO antibody.

Storage

After reconstitution, the EPO antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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