- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
EFNA1 Antibody / Ephrin A1 (F55127)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F55127-0.1ML | In 1X PBS, pH 7.4, with 0.09% sodium azide and 50% glycerol | 0.1 ml | 429 |
| Availability | 1-2 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| UniProt | P20827 |
| Applications | Western Blot : 1:500-1:1000 Immunofluorescence : 1:50-1:100 |
| Limitations | This EFNA1 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Ephrin A1 is a membrane-bound protein that interacts with Eph receptors on neighboring cells, initiating a cascade of signals that regulate cell behavior and movement. This interaction is essential for processes such as cell migration, tissue organization, and synaptic connectivity in the nervous system. Studies have shown that dysregulation of Ephrin A1 signaling can lead to aberrant cell growth, invasion, and metastasis in cancer cells, highlighting its importance in disease progression. One of the key features of Ephrin A1 is its ability to both attract and repel cells, depending on the context and concentration of the molecule. This dual role allows Ephrin A1 to fine-tune cell-cell interactions and ensure proper tissue patterning during development. In the brain, for example, Ephrin A1 guides axonal growth and synapse formation, shaping the intricate neural circuits that underlie cognitive functions. In addition to its role in development, Ephrin A1 has also been implicated in several disease processes. Aberrant expression of EFNA1 has been observed in various types of cancer, including breast, lung, and colon cancer, where it promotes tumor growth and invasion. In neurodegenerative disorders such as Alzheimer's disease, dysregulation of Ephrin A1 signaling disrupts synaptic connectivity and contributes to cognitive decline.
The stated application concentrations are suggested starting points. Titration of the EFNA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 83-115 from the human protein was used as the immunogen for the EFNA1 antibody.
Store the EFNA1 antibody at -20oC.
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
