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Home >> Antibodies >> EDG1 Antibody

EDG1 Antibody (N1039)

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  Catalog No Formulation Size Price (USD)  
Image N1039-100UG 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 429
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N1039-25UG 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 25 ug 219
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EDG1 antibody western blot of human samples
Western blot testing of human samples with EDG1 antibody at 4ug/ml.
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Protein A affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 1901
Applications Western blot : 4-6ug/ml
Limitations This EDG1 antibody is available for research use only.
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Description

EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.

Application Notes

Provided assay concentrations are suggestions only, EDG1 antibody titration may be required for optimal results.

Immunogen

A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.

Storage

Aliquot the EDG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Alternate Names

Endothelial differentiation G protein coupled receptor 1, CD363, Sphingosine 1 phosphate receptor, S1PR1 antibody

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