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Home >> Antibodies >> E-Selectin Antibody

E-Selectin Antibody (F46199)

  Catalog No Formulation Size Price (USD)  
Image F46199-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F46199-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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E-Selectin antibody western blot analysis in NCI-H460 lysate. Predicted molecular weight: 64-115 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P16581
Applications Western blot : 1:1000
Limitations This E-Selectin antibody is available for research use only.
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Description

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Application Notes

Titration of the E-Selectin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This E-Selectin antibody was produced from rabbits immunized with a human partial recombinant protein.

Storage

Aliquot the E-Selectin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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