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Home >> Antibodies >> DSP Antibody / Desmoplakin

DSP Antibody / Desmoplakin (RQ6932)

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  Catalog No Formulation Size Price (USD)  
Image RQ6932 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of human PC-3 cells with DSP antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= DSP antibody.
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Flow cytometry testing of human PC-3 cells with DSP antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= DSP antibody.
Western blot testing of human HepG2 cell lysate with DSP antibody at 0.5ug/ml. Predicted molecular weight: ~332 kDa (isoform DPI), ~260 kDa (isoform DPII), ~279 kDa (isoform DPIa).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P15924
Applications Western blot : 0.5-1 ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This DSP antibody is available for research use only.
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Description

Desmoplakin is a protein in humans that is encoded by the DSP gene. This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the DSP antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids N69-H2195) was used as the immunogen for the DSP antibody.

Storage

After reconstitution, the DSP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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