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Home >> Antibodies >> DSG3 Antibody / Desmoglein 3

DSG3 Antibody / Desmoglein 3 [clone rDSG3/8611] (V4569)

  Catalog No Formulation Size Price (USD)  
Image V4569-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4569-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4569SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human skin tissue with DSG3 antibody (clone rDSG3/8611). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free DSG3 antibody (clone rDSG3/8611) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rDSG3/8611
Purity Protein A/G affinity
UniProt P32926
Localization Cell surface
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This DSG3 antibody is available for research use only.
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Description

Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This mAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.

Application Notes

Optimal dilution of the DSG3 antibody should be determined by the researcher.

Immunogen

A recombinant partial protein sequence (within amino acids 300-500) from the human protein was used as the immunogen for the DSG3 antibody.

Storage

Aliquot the DSG3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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