- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
DRP1 Antibody / Dynamin-related protein 1 / DNM1L (F53331)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F53331-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
|
F53331-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | O00429 |
| Applications | Western blot : 1:1000 |
| Limitations | This DRP1 antibody is available for research use only. |
|
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Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. [UniProt]
Titration of the DRP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This DRP1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 557-590 amino acids from the C-terminal region of human DRP1/DNM1L.
Aliquot the DRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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