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- Tel: 858.663.9055
- Email: info@nsjbio.com
Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
Optimal dilution of the DMRT1 antibody should be determined by the researcher.
Amino acids RDCQCKKCNLIAERQRVMAAQVALRRQQAQE of human DMRT1 were used as the immunogen for the DMRT1 antibody.
After reconstitution, the DMRT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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