- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CYP3A4 Antibody / Cytochrome P450 3A4 [clone ACDE-3] (RQ5252)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5252 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | ACDE-3 |
| Purity | Affinity purified |
| UniProt | P08684 |
| Applications | Western blot : 1:1000-1:5000 |
| Limitations | This CYP3A4 antibody is available for research use only. |
|
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Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.
Optimal dilution of the CYP3A4 antibody should be determined by the researcher.
A synthetic peptide specific to human Cytochrome P450 3A4 / CYP3A4 was used as the immunogen for the CYP3A4 antibody.
Store the CYP3A4 antibody at -20oC.
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