- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CYP1A1 Antibody (F50940)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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F50940-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F50940-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P04798 |
| Localization | Cytoplasmic, membrane |
| Applications | Western blot : 1:1000 Immunofluorescence : 1:10-1:50 IHC (Paraffin) : 1:10-1:50 |
| Limitations | This CYP1A1 antibody is available for research use only. |
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CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk.
Titration of the CYP1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 252-280 from the human protein was used as the immunogen for this CYP1A1 antibody.
Aliquot the CYP1A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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