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Home >> Antibodies >> CXCR6 Antibody

CXCR6 Antibody (R31194)

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Image R31194 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of CXCR6 antibody and Lane 1: rat brain; 2: (r) testis; 3: (r) spleen; 4: mouse brain; 5: (m) testis; Expected/observed molecular weight: ~39kDa.
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Western blot testing of CXCR6 antibody and Lane 1: rat brain; 2: (r) testis; 3: (r) spleen; 4: mouse brain; 5: (m) testis; Expected/observed molecular weight: ~39kDa.
IHC-P: CXCR6 antibody testing of rat spleen tissue
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q9EQ16
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Limitations This CXCR6 antibody is available for research use only.
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    Pred. Reactivity : Mouse, Rat, Dog

Description

Chemokine, CXC Motif, Receptor 6, also known as STRL33 and Bonzo, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing the protein showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that the proteinb may be important in the trafficking of effector T cells mediating type-1 inflammation.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the CXCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of mouse CXCR6 (EDSSKTCSASHNVETTSMFQL) was used as the immunogen for this CXCR6 antibody.

Storage

After reconstitution, the CXCR6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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