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Chemokine(C-X3-C motif) ligand 1 is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al.(1997) identified a 7-transmembrane high-affinity receptor(CX3CR1; 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine.
The stated application concentrations are suggested starting amounts. Titration of the CX3CL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the N-terminus of mouse CX3CL1 (CADPKEKWVQDAMKHLDHQ) was used as the immunogen for this CX3CL1 antibody (100% rat homology).
After reconstitution, the CX3CL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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