- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CRM1 Antibody / XPO1 / Exportin 1 [clone AEFD-24] (RQ4719)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ4719 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AEFD-24 |
| Purity | Affinity purified |
| UniProt | O14980 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This CRM1 antibody is available for research use only. |
|
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Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Optimal dilution of the CRM1 antibody should be determined by the researcher.
A synthetic peptide specific to human CRM1 / XPO1 was used as the immunogen for the CRM1 antibody.
Store the CRM1 antibody at -20oC.
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