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Home >> Antibodies >> CPT1A Antibody / CPT1-L

CPT1A Antibody / CPT1-L (F48084)

  Catalog No Formulation Size Price (USD)  
Image F48084-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48084-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of CPT1A antibody and Y79 lysate. Predicted molecular weight ~86kDa.
IHC data of FFPE cow lactation tissue tested with CPT1A antibody (left) and without primary Ab (right). This data was kindly offered by Hideaki Hayashi, University of Bern, Switzerland.
Availability 1-3 business days
Species Reactivity Human, Bovine
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P50416
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This CPT1A antibody is available for research use only.
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Description

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.

Application Notes

Titration of the CPT1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 606-636 from the human protein was used as the immunogen for this CPT1A antibody.

Storage

Aliquot the CPT1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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