- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Connexin 43 Antibody (F44391)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F44391-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F44391-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Bovine, Xenopus |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P17302 |
| Applications | Western blot : 1:1000 IHC (Paraffin) : 1:50-1:100 |
| Limitations | This Connexin 43 antibody is available for research use only. |
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Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.
Titration of the Connexin 43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 107-138 from the human protein was used as the immunogen for this Connexin 43 antibody.
Aliquot the Connexin 43 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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