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Home >> Antibodies >> cIAP2 Antibody

cIAP2 Antibody (F49443)

  Catalog No Formulation Size Price (USD)  
Image F49443-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49443-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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cIAP2 antibody western blot analysis in A549 lysate
cIAP2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q13489
Localization Cytoplasmic
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This cIAP2 antibody is available for research use only.
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Description

BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.

Application Notes

Titration of the cIAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 101-131 from the human protein was used as the immunogen for this cIAP2 antibody.

Storage

Aliquot the cIAP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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