- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CHK1 Antibody / CHEK1 [clone AAF-3] (RQ4708)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ4708 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human, Rat |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AAF-3 |
| Purity | Affinity purified |
| UniProt | O14757 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This CHK1 antibody is available for research use only. |
|
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The protein encoded by CHEK1 belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. [RefSeq]
Optimal dilution of the CHK1 antibody should be determined by the researcher.
A synthetic peptide specific to human CHK1 / CHEK1 was used as the immunogen for the CHK1 antibody.
Store the CHK1 antibody at -20oC.
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