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Home >> Antibodies >> CHK1 Antibody

CHK1 Antibody (F48011)

  Catalog No Formulation Size Price (USD)  
Image F48011-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48011-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Chk1 antibody western blot analysis in (1) HeLa cell line and (2) mouse thymus tissue lysate. Predicted molecular weight ~54kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt O14757
Applications Western blot : 1:1000
Limitations This CHK1 antibody is available for research use only.
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Description

Checkpoint kinase 1, commonly referred to as CHK1 is an serine/threonine-specific protein kinase that in humans, is encoded by the CHEK1 gene. CHK1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death to prevent damaged cells from progressing through the cell cycle.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the CHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 258-287 from the human protein was used as the immunogen for this CHK1 antibody.

Storage

Store at 4oC for up to one month. For long term, aliquot the CHK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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