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- Tel: 858.663.9055
- Email: info@nsjbio.com
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CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Titration of the CEBPB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 271-298 from the human protein was used as the immunogen for this CEBPB antibody.
Aliquot the CEBPB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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